MODELLING THE IMPACT OF TEMPERATURE UNDER CLIMATE CHANGE SCENARIOS ON NATIVE AND INVASIVE VASCULAR VEGETATION ON THE ANTARCTIC PENINSULA AND SURROUNDING ISLANDS

Modelling the Impact of Temperature under Climate Change Scenarios on Native and Invasive Vascular Vegetation on the Antarctic Peninsula and Surrounding Islands

There are only two species of native vascular plants found on the Antarctic Peninsula and the surrounding islands, Deschampsia Antarctica, and Colobanthus quitensis.Poa annua, a successful invasive species, poses a threat to D.antarctica and C.quitensis.This region may experience extreme changes in biodiversity due to climate change over the next 1

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Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in maladaptive renal repair in mice and humans.Using single-cell transcriptomic and mouse genetic approaches, we show that proximal tubular (PT) cells develop a molecularly distinct, pro-inflammatory stat

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A pan-tumor-siRNA aptamer chimera to block nonsense-mediated mRNA decay inflames and suppresses tumor progression

Immune-checkpoint blockade (ICB) therapy has changed the clinical outcome of many types of aggressive tumors, but there still remain many cancer patients that do not respond to these treatments.There is an unmet need to develop a feasible clinical Microwaves therapeutic platform to increase the rate of response to ICB.Here we use a previously descr

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